Don't Miss the Connection: The Role of RAF1 and ROKα in RAS-Driven Cancers

Cancer caused by a mutant KRAS gene is dependent on the presence of one of its downstream effectors, RAF1 (aka CRAF), but not on ARAF or BRAF. Kinase-independent interaction of RAF1 with ROKα accounts for at least some of this dependence.

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader https://ift.tt/2DVNI3L