Improved Speech Perception in Cochlear Implant Users With Interleaved High-Rate Pulse Trains

Objective: Electrical stimulation with a cochlear implant (CI) elicits abnormally high neural synchrony, which poses significant challenges for speech perception. Previous investigations showed that constant-amplitude high-rate pulse trains (HRPs) desynchronize neural responses and improve stimulus encoding. The study objective was to investigate the effects of HRP on speech perception in adult CI users. Study Design: Prospective, within-subject design. Setting: Tertiary CI center. Patients: Ten adult CI recipients. Intervention: Sentence stimuli were created by modifying a basic continuous interleaved sampling (CIS) strategy (1,000 pulses per second; pps) with interleaved biphasic pulse trains (3,000 pps) on even electrodes. Institute of Electrical and Electronics Engineers sentences in quiet and in noise were tested without HRP, and with HRPs of various stimulation levels. Main Outcome Measure: Sentence perception in percent correct was calculated for all conditions. The highest speech perception score with HRP stimulation was defined as "max-HRP." Results: Group analyses showed significantly improved sentence perception in background noise with HRPs (p 

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader https://ift.tt/2EFEU2n