Abstract Asthma affects children related to trace elements. Our aim was to investigate the levels of trace elements using laser-induced breakdown spectroscopy (LIBS). The study included 120 children aged 4–12 years from both sexes. They were divided into three groups: Group 1 of 40 children was diagnosed as cases of controlled asthma. Group 2 consisted of 40 children diagnosed as cases of uncontrolled asthma. Group 3 consisted of 40 children as normal control. Asthmatic children...
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Abstract Since recently, a number of innovative polarization-based optical imaging modalities have been introduced and extensively used in various biomedical applications, with an ultimate aim to attain the practical tool for the optical biopsy and functional characterization of biological tissues. The techniques utilize polarization properties of light and Mueller matrix mapping of microscopic images of histological sections of biological tissues or polycrystalline films of...
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Abstract Based on two separate randomized controlled trials (RCTs) on traditional Chinese medicine (TCM) moxibustion and 10.6-μm infrared laser moxibustion in treating knee osteoarthritis (OA), we did an indirect and preliminary comparison of the effects of the 10.6-μm laser moxibustion with the traditional moxibustion for knee osteoarthritis. The objective was to see whether the laser moxibustion is non-inferior to the traditional moxibustion in alleviating symptoms of knee...
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Abstract In view of the limitations of bone reconstruction surgeries using autologous grafts as a gold standard, tissue engineering is emerging as an alternative, which permits the fabrication and improvement of scaffolds to stimulate osteogenesis and angiogenesis, processes that are essential for bone repair. Polymers are used to mimic the extracellular bone matrix and support cell growth. In addition, bone neoformation can be induced by external factors such as laser irradiation,...
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Abstract Skin photoaging manifests deeper wrinkles and larger pore size. Various lasers have been tried for rejuvenation of photoaging skin, and the quasi-long-pulsed 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser is one promising treatment option. New types of laser device are emerging, including devices operating with picosecond pulse duration combined with a microlens array, which are regarded as a new breakthrough for skin rejuvenation. We aimed to evaluate the...
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Abstract To date, there is no compilation of evidence-based information associating photobiomodulation effect and salivary glands. This systematic review aims to assess photobiomodulation effect of low intensity laser on salivary glands in the presence of systemic diseases. MEDLINE databases were searched in duplicate through December 2018. In vivo studies and clinical trials were included if photobiomodulation was performed in salivary glands of animal (rat or mice) or human...
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Πυρετός, δύσπνοια, παραγωγικός βήχας, ανοσμία… Η επιστημονική κοινότητα βρέθηκε αντιμέτωπη με σειρά συμπτωμάτων που συνδέονται με τον νέο κορωνοϊό και τη νόσο Covid-19 που προκαλεί. Υπάρχει ωστόσο ένα σύμπτωμα που εμφανίζει ένας στους δύο ασθενείς. Σύμφωνα με τα ευρήματα της έρευνας από ομάδα του Πανεπιστημίου του Τολέδο, τα οποία δημοσιεύτηκαν στο Gastroenterology, οι μισοί σχεδόν ασθενείς με CoVid-19 βιώνουν αλλαγές στην αίσθηση της γεύσης τους. Το εύρημα κρίνεται σημαντικό καθώς, κατά τον επικεφαλής...
Thu May 28, 2020 15:57
Abstract Coronavirus disease 2019 (COVID‐19), is responsible for at least 2,546,527 cases and 175,812 deaths as of April 21, 2020. Psoriasis and atopic dermatitis are common, chronic, inflammatory skin conditions, with immune dysregulation as a shared mechanism; therefore, mainstays of treatment include systemic immunomodulating therapies. It is unknown whether these therapies are associated with increased to COVID‐19 susceptibility or worse outcomes in infected patients. In this review, we discuss...
Wed May 27, 2020 11:44
Abstract Immunosuppressive and immunomodulatory therapies are important in dermatology, but indications are influenced by SARS‐CoV‐2. We will focus on are skin disorders such as autoimmune connective tissue disorders, neutrophilic dermatoses and vasculitis. Immunomodulators such as colchicine and antimalarials can easily be preferred taking their beneficial effects on Covid‐19 into consideration and also given their wide spectrum of action. Among the conventional therapies, methotrexate, azathioprine...
Wed May 27, 2020 11:38
Abstract SARS‐COV‐2 is a highly virulent positive‐sense single stranded RNA virus that spreads rapidly via respiratory droplets, causing severe acute respiratory syndromes with significant mortality and morbidity. Currently 210 countries and territories are affected around the world with a reported 2.6 million confirmed cases.1 The COVID 19 pandemic has changed the way patients attend their specialist appointments and receive medical care. Whilst some specialist clinics have closed we have implemented...
Wed May 27, 2020 11:24
Elastosis perforans serpiginosa induced by D‐penicillamine treated with cyclosporine and allopurinol
ABSTRACT Elastosis perforans serpiginosa (EPS) is a rare condition within the group of perforating dermatoses. It is characterized by the synthesis of anomalous elastic fibres that are eliminated through perforating channels (transepidermal elimination). It is classified into three subtypes. One of them is drug‐induced by prolonged treatment with D‐penicillamine. This drug is a heavy metal chelator used to treat diseases such as rheumatoid arthritis, cystinuria and Wilson's disease. Years of treatment...
Wed May 27, 2020 11:19
Abstract Background The coronavirus disease 2019 is currently of global concern. Cancer patients are advised to stay at home in case of potential infection, which may cause delays of routine diagnosis and necessary treatment. How colorectal surgeons should manage this during the epidemic remains a big challenge. Objective To evaluate the feasibility of routine colorectal surgery during coronavirus disease 2019 and to offer some Chinese recommendations to colorectal surgeons throughout the...
Thu May 28, 2020 22:54
Abstract Objectives The diploic channels are bony passages of veins, running within frontal, parietal, and occipital bones. In this study, we investigate ontogenetic changes of these channels in a sample of nonadult and adult modern humans. Materials and methods Using computed tomography scans of dried crania, we provide quantitative comparisons of lumen size, branch length, volume, and vascular asymmetries, and correlations with age, cranial size, and bone thickness. Results The...
Thu May 28, 2020 22:28
ABSTRACT Purpose To compute the effect of ambient light illuminance settings on the mesh quality of the digital scans accomplished in a subject. Material and methods A subject was recruited. The maxillary dentition did not present any dental restoration. A prosthodontist recorded different complete‐arch maxillary digital scans by using an IOS (TRIOS 3; 3Shape) under 4 different illuminance light conditions namely chair light at 10 000‐lux illuminance (CL group), room light at 1000‐lux illuminance...
Thu May 28, 2020 19:03
Abstract Background The diagnostics of primary aldosteronism (PA) are usually carried out in patients taking antihypertensive medications. We compared hemodynamics between medicated PA, medicated essential hypertension (EH), never‐medicated EH, and normotensive controls (n=130 in all groups). Methods The hypertensive groups were matched for age (53 years), sex (84 male/46 female), and body mass index (BMI) (30 kg/m2); normotensive controls had similar sex distribution (age 48...
Thu May 28, 2020 20:02
https://onlinelibrary.wiley.com/doi/full/10.1111/joim.13098Content List ‐ Read more articles from the symposium: “Mitochondria in human disease”. Abstract Mitochondrial medicine is a field that expanded exponentially in the last 30 years. Individually rare, mitochondrial diseases as a whole are probably the most frequent genetic disorder in adults. The complexity of their genotype–phenotype correlation, in terms of penetrance and clinical expressivity, natural history and diagnostic...
Thu May 28, 2020 13:01
Abstract Renin‐angiotensin system (RAS) blockers are extensively used worldwide to treat many cardiovascular disorders, where they are effective in reducing both mortality and morbidity. These drugs are known to induce an increased expression of Angiotensin Converting Enzyme 2 (ACE2). ACE2 acts as receptor for the novel SARS‐Coronavirus‐2 (SARS‐CoV‐2) which raising the important issue of possible detrimental effects that RAS blockers could exert on the natural history and pathogenesis...
Wed May 27, 2020 17:31
Cover Image © Andrey Prokhorov/iStockphoto
Tue May 26, 2020 16:14
Abstract Loeys‐Dietz syndrome is a heritable disorder of the connective tissue leading to multisystem involvement including craniofacial features, skeletal abnormalities, cutaneous findings and early‐onset and aggressive disease of the aorta and its branches. There are multiple types of Loeys‐Dietz syndrome related to pathogenic variants in TGFBR1 , TGFBR2 , SMAD3 , TGFB2 , and TGFB3 . Individuals with Loeys‐Dietz syndrome may be misdiagnosed as having Marfan syndrome due to shared phenotypic features...
Thu May 28, 2020 12:32
Abstract Pathogenic variants in components of the minor spliceosome have been associated with several human diseases. Recently, it was reported that biallelic RNPC3 variants lead to severe isolated growth hormone deficiency and pituitary hypoplasia. The RNPC3 gene codes for the U11/U12‐65K protein, a component of the minor spliceosome. The minor spliceosome plays a role in the splicing of minor (U12‐type) introns, which are present in ~700–800 genes in humans and represent about 0.35% of all introns....
Thu May 28, 2020 12:32
Thu May 28, 2020 21:09
Background In advanced non–small cell lung cancer (NSCLC), cytologic specimens from transbronchial needle aspiration (TBNA) or transthoracic needle aspiration are often the only cancer tissue material available for the analysis of programmed death ligand 1 (PD‐L1) expression. This study was aimed at assessing the concordance of PD‐L1 expression in histologic and cytologic samples and at evaluating interobserver agreement on specimens in this setting. Methods One hundred and thirty‐eight specimens...
Thu May 28, 2020 15:52
Abstract The COVID-19 is a global pandemic. Its rapid dissemination and serious course require a novel approach to healthcare practices. Severe disease progression is often associated with the development of the Acute Respiratory Distress Syndrome and may require some form of respiratory support, including endotracheal intubation, mechanical ventilation, and enteral nutrition through a nasogastric tube. These conditions increase the risk of dysphagia, aspiration, and aspiration...
Thu May 28, 2020 03:00
The current study has been conducted to evaluate the effect of different processing techniques on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging capacity and the gastroprotective potential of Chenopodium quinoa red seeds in acute gastric injury induced by absolute ethanol in rats. Seven groups of female Sprague Dawley rats were assigned to normal and absolute ethanol (absolute EtOH) groups, given distilled water, reference control omeprazole (OMP, 20 mg/kg), pressure-cooked quinoa seeds (QP,...
Thu May 28, 2020 17:50
Background. Periodontal disease is a public health problem and is strongly associated with systemic diseases; however, its worldwide distribution is not fully understood. Objective. To evaluate global data of periodontal disease: (1) among adolescents, adults, and older population and (2) in low-, middle-, and high-income countries. Methods. This ecological study included data of periodontal disease from the World Health Organization’s data bank which are based on the Community Periodontal Index...
Thu May 28, 2020 17:50
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