Does surgical fragmentation of odontogenic keratocystic capsule interfere with the recurrence rate?

Publication date: Available online 13 October 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Natália Batista Daroit, Rúbia da Rocha Vieira, Fernanda Visioli, Fabio Del Moro Maito, Márcia Gaiger de Oliveira, Pantelis Varvaki Rados
PurposeThe investigators hypothesized that fragmentation of the cystic capsule during surgery influences the recurrence rate of odontogenic keratocysts (OKC) regardless of the treatment modality chosen.MethodsThis retrospective study reviewed cases diagnosed as odontogenic keratocysts on histopathological examination at the Oral Pathology Department between 1991 and 2013. Fragmentation data were obtained from the records of the Oral Surgical Department.ResultsFragmentation of the capsules of OKCs during surgery did not affect recurrence, irrespective of the chosen treatment modality. Addition of techniques such as cryotherapy lowered the risk of recurrence of OKCs (p = 0.013) when compared with the risk of recurrence of OKCs after enucleation. Furthermore, patients with associated nevoid basal cell carcinoma syndrome (NBCCS) had a higher recurrence rate compared to those with no associated syndrome (p = 0.033).ConclusionFragmentation of the cystic capsule does not play an important role in the rate of OKC recurrence. The rate of recurrence can be modified by using additional strategies such as cryotherapy.



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