Source:Sleep Medicine
Author(s): Rosemary SC. Horne, Genevieve Shandler, Knarik Tamanyan, Aidan Weichard, Alexsandria Odoi, Sarah N. Biggs, Margot J. Davey, Gillian M. Nixon, Lisa M. Walter
BackgroundUp to 50% of overweight/obese children have obstructive sleep apnea (OSA) compared to up to 6% of normal weight children. We compared cardiovascular variables between normal weight and overweight/obese children with and without OSA, and controls.MethodsSeventy-four referred children and 24 normal weight non-snoring controls (8-18 years) were recruited. Referred children were grouped according to their obstructive apnea hypopnea index (OAHI): OSA (>1 event/h) or primary snoring (PS ≤1 event/h) and whether they were normal weight (BMI z-score <1.04) or overweight/obese (BMI z-score ≥ 1.04). Wake blood pressure and heart rate and pulse transit time (PTT, an inverse continuous surrogate measure of blood pressure) during sleep were recorded.ResultsWake blood pressure was higher in the overweight/obese OSA group compared to the control, normal weight PS and overweight/obese PS groups (P<0.05 for all). During sleep, blood pressure and heart rate were elevated in the overweight/obese OSA group compared to non-snoring controls (p<0.05). More children who were overweight/obese had reduced blood pressure and heart rate dipping from wake to sleep compared to normal weight children. BMI z-score predicted heart rate and PTT when asleep and both age and BMI z-score predicted blood pressure when awake.ConclusionThis study showed that BMI has both combined and independent effects on blood pressure and heart rate in children with OSA. We have previously shown that treatment of OSA reduces blood pressure and suggest that treatment of OSA in the growing number of overweight/obese children may improve cardiovascular outcomes.
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2g7MQTC
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου