Changes in regulatory B cell levels in bone marrow, blood and sputum of asthmatics following inhaled allergen challenge

Publication date: Available online 6 December 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): John-Paul Oliveria, Amani I. El-Gammal, Michelle Yee, Caitlin D. Obminski, Tara X. Scime, Rick M. Watson, Karen Howie, Paul M. O'Byrne, Roma Sehmi, Gail M. Gauvreau

Teaser

Capsule Summary: Following allergen exposure in the airways of subjects with allergic asthma, Bregs appear to efflux from the bone marrow and accumulate in the lungs with a possible role in dampening local inflammatory responses.


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