Intrarectal fixative for positioning of the prostate for intensity modulated radiotherapy

Janos Stumpf, Subathira Balasundaram, P. G. G. Kurup, Rathnadevi Ramadas, Murali Venkatraman, Karthikeyan Perumal

Journal of Cancer Research and Therapeutics 2017 13(6):1050-1052

Dose escalation improves local control in carcinoma prostate, but rectal toxicity remains a concern. Various techniques have been there to reduce the dose to the rectum. Mobility of the prostate results in a necessary expansion of the target volume. We describe a new intrarectal fixative, developed in-house with transrectal ultrasonography through the fixative itself for localization of the organ by reporting a case with early carcinoma prostate. Concerns of rectal toxicity limit dose escalation in the treatment of prostate cancer. Intra- and interfraction prostate motion is a concern in dose conformity techniques. The intrarectal fixative system developed in-house physically separates the prostate and rectum during radiation treatment. Thus, both intra- and inter-fractional movement of the organ are addressed, therefore planning target volume expansion can be kept minimal.

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