Steroid-responsive encephalopathy in autoimmune thyroiditis: A diagnostic enigma?

Balram Sharma, Vijay Kumar Bhavi, Hardeva Ram Nehra, Anshul Goyal, Sanjay Saran, Sandeep Kumar Mathur

Thyroid Research and Practice 2018 15(1):52-55

Hashimoto's encephalopathy or steroid-responsive encephalopathy associated with autoimmune thyroiditis is a neuroendocrine disorder of unknown cause associated with thyroid autoimmunity. We report case of a 61-year-old male, previously healthy, who developed a subacute onset of declining higher mental functions. Serologic studies demonstrated the high levels of antithyroid antibodies. Electroencephalographic, cerebrospinal fluid, and magnetic resonance image findings were normal, consistent with Hashimoto's encephalopathy. It is a diagnosis of exclusion once the detailed neurology evaluations were done. This unusual disorder is often underrecognized because of the multiple and protracted neurocognitive manifestations; therefore, it is important to be aware of this clinical manifestations to make a correct diagnosis and favorable outcome.

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