Source:Sleep Medicine
Author(s): Richard Schulz, Fabian Bischoff, Wolfgang Galetke, Henning Gall, Jörg Heitmann, Andrea Hetzenecker, Markus Laudenburg, Till Jonas Magnus, Georg Nilius, Christina Priegnitz, Winfried Randerath, Maik Schröder, Marcel Treml, Michael Arzt
ObjectivesErectile dysfunction (ED) is highly prevalent in obstructive sleep apnea (OSA), however, the effect of continuous positive airway pressure (CPAP) therapy on erectile function has not yet been thoroughly investigated in these patients.MethodsNinety-four men with severe OSA (ie with an apnea-hypopnea-index ≥ 30/h of sleep) were prospectively evaluated for the presence and severity of ED before and after 6-12 months of CPAP therapy. The abbreviated version of the International Index of Erectile Function, ie the IIEF-5, was used to rate erectile function. Furthermore, all study participants responded to standard questionnaires of daytime sleepiness (Epworth Sleepiness Scale), quality of life (WHO Wellbeing 5 questionnaire) and depression (Major Depression Inventory).ResultsED as defined by an IIEF-5 score of ≤ 21 was present in 64 patients (ie 68.1%). CPAP treatment significantly improved erectile function in those patients suffering from moderate and severe ED. Additionally, a trend for a correlation between the improvement of erectile function under CPAP and the hours of its use was observed. Finally, this effect was associated with larger improvements of quality of life in affected patients.ConclusionsED is very frequent in men with severe OSA and can at least partly be reversed by long-term CPAP therapy in most seriously affected patients. The beneficial effect on erectile function may depend on CPAP compliance and is accompanied by improvements of quality of life. Randomized controlled trials are needed to confirm these findings.
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader https://ift.tt/2GLVu6G
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