Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case.

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Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case.

Mol Clin Oncol. 2017 Aug;7(2):288-294

Authors: Fornaro R, Salerno A, Filip DC, Caratto E, Caratto M, Casaccia M

Abstract
Schwannomas are benign tumours that originate from the myelin sheath of peripheral nerves. They are characterised by a slow growth tendency. Benign schwannomas represent 35% of the head and neck district tumours. Hypoglossal schwannomas account for 5% of non-vestibular schwannomas, and malignant schwannomas occur very rarely. In the present case report, the case of a 49-year-old man who presented with paraesthesias in the left parotid and submandibular region, associated with sensation of foreign bodies and dysphagia for solids, is described. A clinical examination revealed the presence of an ovoid palpable mass in the lateral-cervical region of the neck. The patient subsequently underwent excisional surgery, and neuropathological evaluation of the specimen confirmed the diagnosis of benign schwannoma with Antoni areas A and B. Despite the rarity of schwannomas, this condition should be considered in differential diagnoses for masses localised in the neck, as in cases where they reach considerable sizes (>3 cm in diameter). Surgery therefore represents the first-choice treatment.

PMID: 28781804 [PubMed]

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