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Adjuvant Therapies in Food Immunotherapy.
Immunol Allergy Clin North Am. 2018 Feb;38(1):89-101
Authors: Loh W, Tang M
Abstract
Finding an effective curative treatment for food allergy is a research priority. Although oral immunotherapy (OIT) is effective at inducing desensitization, the temporary nature of this effect and high rates of adverse reactions have highlighted a need for novel strategies to improve tolerance induction and safety. One such strategy is the use of an adjuvant together with food immunotherapy to either suppress allergic reactions and/or modulate the underlying allergic immune response. In particular, the use of bacterial adjuvants seems to be a promising means of enhancing OIT-induced sustained unresponsiveness and warrants further investigation.
PMID: 29132677 [PubMed - in process]
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