Ewing’s Sarcoma of the Maxillofacial Region In Greek Children: Report of 6 Cases and Literature Review

Ewing's sarcoma (ES) is the second most common primary bone tumor in children and adolescents after osteosarcoma, initially described by Ewing in 1921 as an undifferentiated tumor involving the diaphysis of long bones that, unlike osteosarcoma, was radiation sensitive (Thorn et al. 2016). It accounts for approximately 3% of pediatric cancers and is most commonly diagnosed during the second decade of life, with a male to female ratio of 1.3:1 (Bernstein et al. 2006; Grevener et al. 2016). It usually affects the pelvis and long bones; extraskeletal tumors are rare in children (Osborn et al.

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