Gapo Syndrome -A Rare Cause of Osteomyelitis of Jaws; Report of Four Cases With Brief Review of Literature

Publication date: Available online 12 December 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Rudrayya S. Puranik., Surekha R. Puranik, Neelakamal Hallur, Deepak Venkatesh
The GAPO syndrome is characterised by growth retardation, alopecia, pseudoanodontia and ophthalmic abnormalities. This very rarely reported syndrome is known to affect various ethnic groups and may present with manifestations other than the usually reported. Pseudoanodontia is a rare clinico-radiologic manifestation known to be always associated with GAPO syndrome. Osteomyelitis of jaws is a less common disease that is usually attributed to odontogenic causes. This case report illustrates osteomyelitis of the mandible in a patient with GAPO syndrome. Further, an additional three cases of GAPO in the patient's family, with special emphasis on oral mucosal changes and pseudoanodontia, are discussed.



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