Risk factors for granuloma formation in children induced by tracheobronchial foreign bodies.

Risk factors for granuloma formation in children induced by tracheobronchial foreign bodies.

Int J Pediatr Otorhinolaryngol. 2015 Nov 4;

Authors: Huang Z, Zhou A, Zhang J, Xie L, Li Q

Abstract
OBJECTIVE: The aim of this study was to analyze the risk factors for granuloma formation caused by plant-based tracheobronchial foreign bodies in children, and investigate the underlying pathogenesis.
METHOD: In this retrospective analysis of 153 cases with tracheobronchial foreign bodies (peanuts and watermelon seeds), 35 cases of granuloma formation as granulation group (G), and 118 cases of no granuloma formation as non-granulation group (NG) were studied. Clinical data pertaining to sex (S), age (A), foreign body surface smoothness (SF), foreign body shape (SH), foreign body oil release state (O), the location of foreign bodies (L), and foreign body retention time (T) were collected for statistical analysis.
RESULTS: Univariate analysis showed no significant difference between the two groups (G and NG) with respect to S, A, SH and L. Significant factors based on univariate analysis included SF, O and T. Multivariate logistic regression analysis revealed that SF and T were independent risk factors associated with development of granuloma.
CONCLUSIONS: SF, O and T had relationship with the granuloma formation. Local trauma caused by an irregular and sharp foreign body, and extended period of time represent the main factors causing granuloma formation.

PMID: 26596356 [PubMed - as supplied by publisher]

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