[The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV].

[The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 May;29(10):934-6

Authors: Zhou X, Yu Y, Zhao Y, Wang Y, Liu Z, Liu Q

Abstract
OBJECTIVE: To evaluate the efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV.
METHOD: A total of 63 patients diagnosed with sudden sensorineural hearing loss with BPPV were treated through OPD. Patients were divided into three groups: 20 cases in intratympanic dexamethasone injection as initial treatment (group A); 18 cases in systemic hormone therapy group (group B); 25 cases in intratympanic dexamethasone injection as salvage treatment (group C). In addition, routine drugs were used to all patients.
RESULT: The overall effective rate of group A, B and C in hearing recovery was 60.0%, 38.9% and 48.0%, respectively: (1) No significant difference of hearing recovery was observed among three groups (P > 0.05); (2) A significant difference of hearing recovery was evidenced between group A and C (P < 0.05); (3) A significant difference of hearing recovery was evidenced between group A and C (P < 0.05); (4) No statistically significant difference was found in the hearing recovery between group B and C (P > 0.05).
CONCLUSION: Our data showed that intratympanic dexamethasone should be used as initial therapy for treating the moderate and severe sudden deafness with BPPV.

PMID: 26596013 [PubMed - in process]

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