Subject-Specific Computational Modeling of Evoked Rabbit Phonation.

Subject-Specific Computational Modeling of Evoked Rabbit Phonation.

J Biomech Eng. 2015 Nov 23;

Authors: Chang S, Novaleski CK, Kojima T, Mizuta M, Luo H, Rousseau B

Abstract
When developing high-fidelity computational model of vocal fold vibration for voice production of individuals, one would run into typical issues of unknown model parameters and model validation of individual-specific characteristics of phonation. In the current study, the evoked rabbit phonation is adopted to explore some of these issues. In particular, the mechanical properties of the rabbit's vocal fold tissue are unknown for individual subjects. In the model, we couple a 3D vocal fold model that is based on the MR scan of the rabbit larynx and a simple 1D model for the glottal airflow to perform fast simulations of the vocal fold dynamics. This hybrid 3D/1D model is then used along with the experiment measurement of each individual subject for determination of the vocal fold properties. The vibration frequency and deformation amplitude from the final model are matched reasonably well for individual subjects. The modeling and validation approaches adopted here could be useful for future development of subject-specific computational models of vocal fold vibration.

PMID: 26592748 [PubMed - as supplied by publisher]

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